LIPITOR is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme 12
1)
Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
People with primary hyperlipidemia mainly have high blood levels of LDL cholesterol
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications
It contains the active drug atorvastatin, which also comes in a generic form
Detailed dosage guidelines and administration information for Lipitor (atorvastatin calcium)
If your child’s doctor prescribes Vytorin for HeFH, their starting dose will be
How it works Lipitor is a brand (trade) name for atorvastatin
Atorvastatin, also known by its brand name Lipitor, is a cholesterol medication that can be taken once daily
Concomitant administration of LIPITOR with rifampin, an inducer of cytochrome P450 3A4 and inhibitor of OATP1B1, can lead to variable reductions in plasma concentrations of atorvastatin
It may be given to you for other reasons
Leqvio is not expected to cause drug-drug interactions or to be affected by inhibitors or inducers of cytochrome P450 enzymes or transporters
Keep out of sight and reach of children Statins work by reducing the amount of cholesterol made by the liver and by helping the liver remove cholesterol that is already in the blood
• Monitor serum cholesterol before, about 4 weeks after starting, and fre-
only)
Atorvastatin AUC was significantly increased with concomitant administration of Lipitor 10 mg and cyclosporine 5
This may lead to developing type 2 diabetes
Bile acid sequestrant: Administer medication atorvastatin/ezetimibe 2 hours or more before or 4 hours or more after administering bile acid sequestrant; Cyclosporine, tipranavir plus ritonavir, For others with high cholesterol, medication may also be needed
Food and Drug Administration (FDA) has approved important safety label changes for the class of cholesterol-lowering drugs known as statins
(3) Investigation of pharmacokinetic properties of individual statins disproved the need for all agents to be dosed at bedtime
Food and Drug Administration (FDA): atorvastatin (Lipitor) fluvastatin (Lescol) lovastatin (Mevacor) lovatstatin extended release (Altoprev) pitavastatin (Livalo) pravastatin (Pravachol) rosuvastatin (Crestor) simvastatin (Zocor)
LIPITOR is used: to reduce the risk of: heart attack, stroke, certain types of heart surgery and chest pain in adults who do not have heart disease but have other multiple risk factors for heart disease
The mechanics of the medication decrease cholesterol synthesis in the body, as well as those of other active substances derived from cholesterol